The anti-inflammatory effects of ketoprofen in animal experiments

  • L. M. Wang
  • , A. Toyoshima
  • , S. Mineshita
  • , X. X. Wang
  • , T. Yamamoto
  • , Y. Nomura
  • , L. Yang
  • , Y. Koikei
  • , K. Shiba
  • , Y. Honda

研究成果: ジャーナルへの寄稿記事査読

5 被引用数 (Scopus)

抄録

The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity. The findings in these studies show that ketoprofen inhibits rat paw oedema, suppresses capillary permeability, reduces IL-8 production and increases SOD activity in the acetic-acid-induced inflammatory state. These results would seem to provide a clear rationale for exploring the usefulness of ketoprofen in the treatment of acute and chronic inflammatory diseases.

本文言語英語
ページ(範囲)1-6
ページ数6
ジャーナルDrugs under Experimental and Clinical Research
23
1
出版ステータス出版済み - 1997
外部発表はい

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