TY - JOUR
T1 - On-nerve needle nerve conduction study in the sural nerve
T2 - A new technique for evaluation of peripheral neuropathy
AU - Oh, Shin J.
AU - Hemmi, Shoji
AU - Hatanaka, Yuki
N1 - Publisher Copyright:
© 2014 International Federation of Clinical Neurophysiology.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Objective: The objective of this study was to compare the nerve conduction study (NCS) data by the surface electrode (SE)-NCS versus the on-nerve needle (ONN)-NCS and to assess their clinical usefulness in the diagnosis of peripheral neuropathy. Methods: Sensory compound nerve action potentials (CNAPs) were obtained by the ONN-NCS with needle electrodes placed on the exposed sural nerve during biopsy in 94 patients with peripheral neuropathy. Results: The ONN-NCS is possible in 95% of cases. The ONN-NCS was able to record sensory CNAP in 15% of cases when it was unobtainable in the SE-NCS. The ONN-NCS showed higher amplitude and longer duration of the CNAP but a slower maximum nerve conduction velocity (NCV) than the SE-NCS. The ONN-NCS showed a significantly better concordance with the nerve biopsy findings, especially in demyelinating neuropathy. Conclusion: The ONN-NCS is a better electrophysiological test for the histopathological correlation with nerve biopsy. Significance: The ONN-NCS was able to record sensory CNAP in 15% of cases when it was unobtainable in the SE-NCS.
AB - Objective: The objective of this study was to compare the nerve conduction study (NCS) data by the surface electrode (SE)-NCS versus the on-nerve needle (ONN)-NCS and to assess their clinical usefulness in the diagnosis of peripheral neuropathy. Methods: Sensory compound nerve action potentials (CNAPs) were obtained by the ONN-NCS with needle electrodes placed on the exposed sural nerve during biopsy in 94 patients with peripheral neuropathy. Results: The ONN-NCS is possible in 95% of cases. The ONN-NCS was able to record sensory CNAP in 15% of cases when it was unobtainable in the SE-NCS. The ONN-NCS showed higher amplitude and longer duration of the CNAP but a slower maximum nerve conduction velocity (NCV) than the SE-NCS. The ONN-NCS showed a significantly better concordance with the nerve biopsy findings, especially in demyelinating neuropathy. Conclusion: The ONN-NCS is a better electrophysiological test for the histopathological correlation with nerve biopsy. Significance: The ONN-NCS was able to record sensory CNAP in 15% of cases when it was unobtainable in the SE-NCS.
KW - Electrophysiological test
KW - Nerve conduction test
KW - On-nerve needle nerve conduction
KW - Peripheral neuropathy
KW - Sensory nerve conduction
UR - https://www.scopus.com/pages/publications/84938951133
U2 - 10.1016/j.clinph.2014.12.008
DO - 10.1016/j.clinph.2014.12.008
M3 - 記事
C2 - 25727898
AN - SCOPUS:84938951133
SN - 1388-2457
VL - 126
SP - 1811
EP - 1816
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
IS - 9
ER -