Key roles of Phe¹¹¹² and Ser¹¹¹⁵ in the pore-forming IIIS5-S6 linker of L-type Ca²⁺ channel α_1C subunit (Ca_v1.2) in binding of dihydropyridines and action of Ca²⁺ channel agonists

Shinji Yamaguchi, Boris S. Zhorov, Katsuro Yoshioka, Taku Nagao, Hidenori Ichijo, Satomi Adachi-Akahane

The University of Tokyo
McMaster University
National Institute of Health Sciences Tokyo

研究成果: ジャーナルへの寄稿 › 記事 › 査読

52 被引用数 (Scopus)

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「Key roles of Phe¹¹¹² and Ser¹¹¹⁵ in the pore-forming IIIS5-S6 linker of L-type Ca²⁺ channel α_1C subunit (Ca_v1.2) in binding of dihydropyridines and action of Ca²⁺ channel agonists」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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Key roles of Phe¹¹¹² and Ser¹¹¹⁵ in the pore-forming IIIS5-S6 linker of L-type Ca²⁺ channel α_1C subunit (Ca_v1.2) in binding of dihydropyridines and action of Ca²⁺ channel agonists

フィンガープリント

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science

Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel α1C subunit (Cav1.2) in binding of dihydropyridines and action of Ca2+ channel agonists

フィンガープリント

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science

Key roles of Phe¹¹¹² and Ser¹¹¹⁵ in the pore-forming IIIS5-S6 linker of L-type Ca²⁺ channel α_1C subunit (Ca_v1.2) in binding of dihydropyridines and action of Ca²⁺ channel agonists