Isolation and characterization of atropisomers of seven-membered-ring benzolactams

Hidetsugu Tabata; Naoya Wada; Yuko Takada; Tetsuta Oshitari; Hideyo Takahashi; Hideaki Natsugari

doi:10.1021/jo2008725

Isolation and characterization of atropisomers of seven-membered-ring benzolactams

Hidetsugu Tabata
, Naoya Wada
, Yuko Takada
, Tetsuta Oshitari
, Hideyo Takahashi
, Hideaki Natsugari

薬学部

Teikyo University

研究成果: ジャーナルへの寄稿 › 記事 › 査読

31 被引用数 (Scopus)

抄録

The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.

本文言語	英語
ページ（範囲）	5123-5131
ページ数	9
ジャーナル	Journal of Organic Chemistry
巻	76
号	12
DOI	https://doi.org/10.1021/jo2008725
出版ステータス	出版済み - 17 6月 2011

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10.1021/jo2008725

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Scopusの出版物のリンク

CCDC 835441: Experimental Crystal Structure Determination
Tabata, H. (作成者), Wada, N. (作成者), Takada, Y. (作成者), Oshitari, T. (作成者), Takahashi, H. (作成者) & Natsugari, H. (寄稿者), Cambridge Crystallographic Data Centre, 2012
DOI: 10.5517/ccx1bqz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccx1bqz&sid=DataCite
データセット
CCDC 835439: Experimental Crystal Structure Determination
Tabata, H. (作成者), Wada, N. (作成者), Takada, Y. (作成者), Oshitari, T. (作成者), Takahashi, H. (作成者) & Natsugari, H. (寄稿者), Cambridge Crystallographic Data Centre, 2012
DOI: 10.5517/ccx1bnx, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccx1bnx&sid=DataCite
データセット
CCDC 835440: Experimental Crystal Structure Determination
Tabata, H. (作成者), Wada, N. (作成者), Takada, Y. (作成者), Oshitari, T. (作成者), Takahashi, H. (作成者) & Natsugari, H. (寄稿者), Cambridge Crystallographic Data Centre, 2012
DOI: 10.5517/ccx1bpy, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccx1bpy&sid=DataCite
データセット

引用スタイル

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abstract = "The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.",

author = "Hidetsugu Tabata and Naoya Wada and Yuko Takada and Tetsuta Oshitari and Hideyo Takahashi and Hideaki Natsugari",

year = "2011",

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volume = "76",

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journal = "Journal of Organic Chemistry",

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T1 - Isolation and characterization of atropisomers of seven-membered-ring benzolactams

AU - Tabata, Hidetsugu

AU - Wada, Naoya

AU - Takada, Yuko

AU - Oshitari, Tetsuta

AU - Takahashi, Hideyo

AU - Natsugari, Hideaki

PY - 2011/6/17

Y1 - 2011/6/17

N2 - The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.

AB - The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.

UR - https://www.scopus.com/pages/publications/79958834708

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DO - 10.1021/jo2008725

M3 - 記事

AN - SCOPUS:79958834708

SN - 0022-3263

VL - 76

SP - 5123

EP - 5131

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 12

ER -

Isolation and characterization of atropisomers of seven-membered-ring benzolactams

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データセット

CCDC 835441: Experimental Crystal Structure Determination

CCDC 835439: Experimental Crystal Structure Determination

CCDC 835440: Experimental Crystal Structure Determination

引用スタイル