Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

Mehdi Razzaghi-Abyaneh; Tomoya Yoshinari; Masoomeh Shams-Ghahfarokhi; Mohammad Bagher Rezaee; Hiromichi Nagasawa; Shohei Sakuda

doi:10.1271/bbb.70264

Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G₁ in Aspergillus parasiticus

Mehdi Razzaghi-Abyaneh
, Tomoya Yoshinari
, Masoomeh Shams-Ghahfarokhi
, Mohammad Bagher Rezaee
, Hiromichi Nagasawa
, Shohei Sakuda

The University of Tokyo
Pasteur Institute of Iran
Tarbiat Modarres University
Institute for Research in Forests and Rangelands

研究成果: ジャーナルへの寄稿 › 記事 › 査読

82 被引用数 (Scopus)

抄録

Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G₁ production. It inhibited aflatoxin G ₁ production by Aspergillus parasiticus with an IC₅₀ value of 0.15 μM without inhibiting aflatoxin B₁ production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC₅₀ values of 0.24 and 3.5 μM, respectively.

本文言語	英語
ページ（範囲）	2329-2332
ページ数	4
ジャーナル	Bioscience, Biotechnology and Biochemistry
巻	71
号	9
DOI	https://doi.org/10.1271/bbb.70264
出版ステータス	出版済み - 2007
外部発表	はい

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title = "Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus",

abstract = "Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G 1 production by Aspergillus parasiticus with an IC50 value of 0.15 μM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 μM, respectively.",

keywords = "Aflatoxin, Apiol, Aspergillus parasiticus, Dillapiol, Inhibitor",

author = "Mehdi Razzaghi-Abyaneh and Tomoya Yoshinari and Masoomeh Shams-Ghahfarokhi and Rezaee, \{Mohammad Bagher\} and Hiromichi Nagasawa and Shohei Sakuda",

year = "2007",

doi = "10.1271/bbb.70264",

language = "英語",

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pages = "2329--2332",

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T1 - Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

AU - Razzaghi-Abyaneh, Mehdi

AU - Yoshinari, Tomoya

AU - Shams-Ghahfarokhi, Masoomeh

AU - Rezaee, Mohammad Bagher

AU - Nagasawa, Hiromichi

AU - Sakuda, Shohei

PY - 2007

Y1 - 2007

N2 - Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G 1 production by Aspergillus parasiticus with an IC50 value of 0.15 μM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 μM, respectively.

AB - Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G 1 production by Aspergillus parasiticus with an IC50 value of 0.15 μM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 μM, respectively.

KW - Aflatoxin

KW - Apiol

KW - Aspergillus parasiticus

KW - Dillapiol

KW - Inhibitor

UR - https://www.scopus.com/pages/publications/36148949738

U2 - 10.1271/bbb.70264

DO - 10.1271/bbb.70264

M3 - 記事

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AN - SCOPUS:36148949738

SN - 0916-8451

VL - 71

SP - 2329

EP - 2332

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

IS - 9

ER -

Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

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Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G₁ in Aspergillus parasiticus