肝転移をきたした直腸神経内分泌腫瘍G₁ の₁ 例

A 58-year-old woman presented to our hospital due to bleeding during bowel movements for approximately 5 years. Lower gastrointestinal endoscopy revealed a 40-mm, slightly uneven, yel-lowish, ridge-like lesion that rose steeply from the lower Huston valve. The raised surface was covered with a nontumor mucosa that showed an ulcerated surface. Biopsies from the ulcer mar-gin resulted in the diagnosis of a neuroendocrine tumor (NET). Abdominal computed tomography revealed lateral lymphadenopathy and a calcified liver tumor. We diagnosed the lymphadenopa- thy and liver tumor to be metastatic from the rectal NET and resected the rectal and liver tu mors along with the enlarged lymph nodes during a two-stage surgery. All the resected tissues were pathologically diagnosed as G1 NET. We describe this rare case of G1 NET progressing to a large tumor, with lymphadenopathy and liver metastasis.