[Treatment and prevention of NSAIDs-induced gastrointestinal injury--the role of gastroenterologist].

According to many clinical researches, it is obvious that patients taking NSAIDs including low-dose aspirin have upper GI injury frequently than those without. Recently, the GI event of those medicines becomes more serious clinical problem in Japan in which aging population is getting larger year by year. Evaluation of GI risk and appropriate use of anti -ulcer drugs, especially proton-pump inhibitors, are recommended for the prevention. Additionally, the close communication and cooperation between doctors who prescribe the medicines and gastroenterologists is essential for minimizing such adverse reaction. Here we describe on the role of gastroenterologists on the prevention of GI event caused by NSAIDs and aspirin.