Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

Nobutada Tanaka; Masayuki Nakanishi; Yoshio Kusakabe; Katsura Shiraiwa; Saori Yabe; Yasutomo Ito; Yukio Kitade; Kazuo T. Nakamura

Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

Nobutada Tanaka
, Masayuki Nakanishi
, Yoshio Kusakabe
, Katsura Shiraiwa
, Saori Yabe
, Yasutomo Ito
, Yukio Kitade
, Kazuo T. Nakamura

Showa Medical University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.

Original language	English
Pages (from-to)	281-282
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	48
State	Published - 2004
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

@article{fddbc12348864dfd89a72c0fe757d22b,

title = "Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.",

abstract = "Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.",

author = "Nobutada Tanaka and Masayuki Nakanishi and Yoshio Kusakabe and Katsura Shiraiwa and Saori Yabe and Yasutomo Ito and Yukio Kitade and Nakamura, \{Kazuo T.\}",

year = "2004",

language = "英語",

pages = "281--282",

journal = "Nucleic acids symposium series",

issn = "0261-3166",

publisher = "Oxford University Press",

number = "48",

}

TY - JOUR

T1 - Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

AU - Tanaka, Nobutada

AU - Nakanishi, Masayuki

AU - Kusakabe, Yoshio

AU - Shiraiwa, Katsura

AU - Yabe, Saori

AU - Ito, Yasutomo

AU - Kitade, Yukio

AU - Nakamura, Kazuo T.

PY - 2004

Y1 - 2004

N2 - Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.

AB - Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.

UR - https://www.scopus.com/pages/publications/36048982464

M3 - 記事

C2 - 17150588

AN - SCOPUS:36048982464

SN - 0261-3166

SP - 281

EP - 282

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

IS - 48

ER -

Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

Abstract

UN SDGs

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