TY - JOUR
T1 - Tear film break-up time evaluated by real-time Hartmann-Shack wavefront sensing
AU - Mihashi, Toshifumi
AU - Hirohara, Yoko
AU - Koh, Shizuka
AU - Ninomiya, Sayuri
AU - Maeda, Naoyuki
AU - Fujikado, Takashi
PY - 2006/4
Y1 - 2006/4
N2 - Purpose: To develop a novel method for measuring tear break-up time (BUT) by continuously measuring higher order wavefront aberrations using a Hartmann-Shack (H-S) aberrometer. Methods: Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in six eyes of six normal subjects using an H-S aberrometer. The aberrometry was performed once every second for up to 50s under topical anesthesia. The sequence of the points was divided into two stages, and the BUT was defined as the wavefront border of the stages (WFBUT). The WFBUT was compared with the BUT by the conventional fluorescein method (FLBUT) or by the disruption of placid-ring images (PLBUT). Results: In three eyes, the WFBUT (average, 10.9 ± 1.1s) was shorter than the PLBUT (average, 17.5 ± 2.5s), while in the other three eyes the WFBUT (average, 21.5 ± 2.2s) was longer than PLBUT (average, 8.1 ± 2.2s). The FLBUT was shorter than WFBUT or PLBUT in most cases. Conclusions: The tear break-up time measured by H-S aberrometer may be used as a practical measure of tear break-up.
AB - Purpose: To develop a novel method for measuring tear break-up time (BUT) by continuously measuring higher order wavefront aberrations using a Hartmann-Shack (H-S) aberrometer. Methods: Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in six eyes of six normal subjects using an H-S aberrometer. The aberrometry was performed once every second for up to 50s under topical anesthesia. The sequence of the points was divided into two stages, and the BUT was defined as the wavefront border of the stages (WFBUT). The WFBUT was compared with the BUT by the conventional fluorescein method (FLBUT) or by the disruption of placid-ring images (PLBUT). Results: In three eyes, the WFBUT (average, 10.9 ± 1.1s) was shorter than the PLBUT (average, 17.5 ± 2.5s), while in the other three eyes the WFBUT (average, 21.5 ± 2.2s) was longer than PLBUT (average, 8.1 ± 2.2s). The FLBUT was shorter than WFBUT or PLBUT in most cases. Conclusions: The tear break-up time measured by H-S aberrometer may be used as a practical measure of tear break-up.
KW - Aberration
KW - Break-up time
KW - Hartmann-Shack aberrometer
KW - Tear film
UR - https://www.scopus.com/pages/publications/33645702803
U2 - 10.1007/s10384-005-0289-6
DO - 10.1007/s10384-005-0289-6
M3 - 記事
C2 - 16604380
AN - SCOPUS:33645702803
SN - 0021-5155
VL - 50
SP - 85
EP - 89
JO - Japanese Journal of Ophthalmology
JF - Japanese Journal of Ophthalmology
IS - 2
ER -