Systemic inonotus sp. Infection in a dog

Yu Furusawa; Masashi Takahashi; Tomoko Iwanaga; Akira Yabuki; Rui Kano; Hitoshi Hatai; Wako Sueno; Yasuyuki Endo; Yasuyuki Momoi

doi:10.1292/jvms.19-0455

Systemic inonotus sp. Infection in a dog

Yu Furusawa
, Masashi Takahashi
, Tomoko Iwanaga
, Akira Yabuki
, Rui Kano
, Hitoshi Hatai
, Wako Sueno
, Yasuyuki Endo
, Yasuyuki Momoi

Research output: Contribution to journal › Article › peer-review

Abstract

A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardiwere auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.

Original language	English
Pages (from-to)	779-783
Number of pages	5
Journal	Journal of Veterinary Medical Science
Volume	82
Issue number	6
DOIs	https://doi.org/10.1292/jvms.19-0455
State	Published - Jun 2020
Externally published	Yes

Keywords

Antifungal agent
Dog
Inonotus sp
Systemic mycosis

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10.1292/jvms.19-0455

Cite this

@article{3e43fb39e86f484fb5725c974951f748,

title = "Systemic inonotus sp. Infection in a dog",

abstract = "A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardiwere auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.",

keywords = "Antifungal agent, Dog, Inonotus sp, Systemic mycosis",

author = "Yu Furusawa and Masashi Takahashi and Tomoko Iwanaga and Akira Yabuki and Rui Kano and Hitoshi Hatai and Wako Sueno and Yasuyuki Endo and Yasuyuki Momoi",

note = "Publisher Copyright: {\textcopyright} 2020 The Japanese Society of Veterinary Science.",

year = "2020",

month = jun,

doi = "10.1292/jvms.19-0455",

language = "英語",

volume = "82",

pages = "779--783",

journal = "Journal of Veterinary Medical Science",

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publisher = "Japanese Society of Veterinary Science",

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}

TY - JOUR

T1 - Systemic inonotus sp. Infection in a dog

AU - Furusawa, Yu

AU - Takahashi, Masashi

AU - Iwanaga, Tomoko

AU - Yabuki, Akira

AU - Kano, Rui

AU - Hatai, Hitoshi

AU - Sueno, Wako

AU - Endo, Yasuyuki

AU - Momoi, Yasuyuki

PY - 2020/6

Y1 - 2020/6

N2 - A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardiwere auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.

AB - A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardiwere auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.

KW - Antifungal agent

KW - Dog

KW - Inonotus sp

KW - Systemic mycosis

UR - https://www.scopus.com/pages/publications/85086931417

U2 - 10.1292/jvms.19-0455

DO - 10.1292/jvms.19-0455

M3 - 記事

C2 - 32378518

AN - SCOPUS:85086931417

SN - 0916-7250

VL - 82

SP - 779

EP - 783

JO - Journal of Veterinary Medical Science

JF - Journal of Veterinary Medical Science

IS - 6

ER -

Systemic inonotus sp. Infection in a dog

Abstract

Keywords

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