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Schizencephaly: Clinical and MRI features by

  • Takato Morioka
  • , Shunji Nishio
  • , Kei Hisada
  • , Futoshi Mihara
  • , Hisakazu Ishioka
  • , Yasuhiko Nakamura
  • , Tazuko Nagamatsu
  • , Masashi Fukui
  • Neurological Institute
  • Kyushu University
  • Nagamatsu Neurological Clinic

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We report the clinical and neuroimaging features of 4 cases with schizencephaly. Case 1 had bilateral schizencephaly with open-lip on the right and closedlip on th left. Case 2 had unilateral schizencephaly with closed-lip on the left and subcortical heterotopia on the right. Case 3 had unilateral schizencephaly with closed lip on the left. Case 4 had bilateral closedlip schizencephaly. Although all cases except for Case 3 had bilateral lesions, neurodevelopmental outcome was generally good ; Case 1 and 3 had mild hemiparesis. All patient have epilepsy which are well-controlled with antiepileptic drugs. Thus, the clinical presentation of schizencephaly, even if bilateral lesions, are quite variable.

Original languageEnglish
Pages (from-to)938-944
Number of pages7
JournalBrain and Nerve
Volume51
Issue number11
StatePublished - 1999
Externally publishedYes

Keywords

  • Epilepsy
  • Magnetic resonance imaging
  • Schizencephaly

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