Preoperative evaluation of residual liver function for extended hepatic resection with positron emission tomography and L-[methyl-11C] methionine

Kazunori Otsuki; Takehide Asano; Shinichi Okazumi; Kazuo Enomoto; Wataru Takayama; Yasushi Shinohara; Fumihiko Miura; Kaichi Isono

doi:10.1016/S0928-4346(97)00371-X

Preoperative evaluation of residual liver function for extended hepatic resection with positron emission tomography and L-[methyl-¹¹C] methionine

Kazunori Otsuki, Takehide Asano, Shinichi Okazumi, Kazuo Enomoto, Wataru Takayama, Yasushi Shinohara, Fumihiko Miura, Kaichi Isono

Chiba University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

To evaluate residual liver functional reserve before major hepatectomy, volumetry of the residual liver was measured by computed tomography (CT) and the uptake of L-[methyl-¹¹C] methionine of the residual liver was expressed by differential absorption ratio (DAR) with positron emission tomography (PET). Residual liver functional volume was quantified as the functional volume index (FVI). FVI of 11 normal whole liver was 8697 ±2009 (mean S.D.). Cases, 11, of malignant liver tumors with obstructive jaundice underwent major hepatectomy. FVI of the eight patients (5561 ± 1087) who had good course after operation was significantly higher than that of the other cases (2665 ± 685) died of liver failure (P < 0.005). FVI is a useful index to quantify residual liver functional reserve to avoid liver failure after major hepatectomy.

Original language	English
Pages (from-to)	43-47
Number of pages	5
Journal	Hepatology Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1016/S0928-4346(97)00371-X
State	Published - 1997
Externally published	Yes

Keywords

Hepatic functional reserve
Major hepatectomy
Methionine Amino acid metabolism

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10.1016/S0928-4346(97)00371-X

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title = "Preoperative evaluation of residual liver function for extended hepatic resection with positron emission tomography and L-[methyl-11C] methionine",

abstract = "To evaluate residual liver functional reserve before major hepatectomy, volumetry of the residual liver was measured by computed tomography (CT) and the uptake of L-[methyl-11C] methionine of the residual liver was expressed by differential absorption ratio (DAR) with positron emission tomography (PET). Residual liver functional volume was quantified as the functional volume index (FVI). FVI of 11 normal whole liver was 8697 ±2009 (mean S.D.). Cases, 11, of malignant liver tumors with obstructive jaundice underwent major hepatectomy. FVI of the eight patients (5561 ± 1087) who had good course after operation was significantly higher than that of the other cases (2665 ± 685) died of liver failure (P < 0.005). FVI is a useful index to quantify residual liver functional reserve to avoid liver failure after major hepatectomy.",

keywords = "Hepatic functional reserve, Major hepatectomy, Methionine Amino acid metabolism",

author = "Kazunori Otsuki and Takehide Asano and Shinichi Okazumi and Kazuo Enomoto and Wataru Takayama and Yasushi Shinohara and Fumihiko Miura and Kaichi Isono",

year = "1997",

doi = "10.1016/S0928-4346(97)00371-X",

language = "英語",

volume = "7",

pages = "43--47",

journal = "Hepatology Research",

issn = "0928-4346",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "1",

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TY - JOUR

T1 - Preoperative evaluation of residual liver function for extended hepatic resection with positron emission tomography and L-[methyl-11C] methionine

AU - Otsuki, Kazunori

AU - Asano, Takehide

AU - Okazumi, Shinichi

AU - Enomoto, Kazuo

AU - Takayama, Wataru

AU - Shinohara, Yasushi

AU - Miura, Fumihiko

AU - Isono, Kaichi

PY - 1997

Y1 - 1997

N2 - To evaluate residual liver functional reserve before major hepatectomy, volumetry of the residual liver was measured by computed tomography (CT) and the uptake of L-[methyl-11C] methionine of the residual liver was expressed by differential absorption ratio (DAR) with positron emission tomography (PET). Residual liver functional volume was quantified as the functional volume index (FVI). FVI of 11 normal whole liver was 8697 ±2009 (mean S.D.). Cases, 11, of malignant liver tumors with obstructive jaundice underwent major hepatectomy. FVI of the eight patients (5561 ± 1087) who had good course after operation was significantly higher than that of the other cases (2665 ± 685) died of liver failure (P < 0.005). FVI is a useful index to quantify residual liver functional reserve to avoid liver failure after major hepatectomy.

AB - To evaluate residual liver functional reserve before major hepatectomy, volumetry of the residual liver was measured by computed tomography (CT) and the uptake of L-[methyl-11C] methionine of the residual liver was expressed by differential absorption ratio (DAR) with positron emission tomography (PET). Residual liver functional volume was quantified as the functional volume index (FVI). FVI of 11 normal whole liver was 8697 ±2009 (mean S.D.). Cases, 11, of malignant liver tumors with obstructive jaundice underwent major hepatectomy. FVI of the eight patients (5561 ± 1087) who had good course after operation was significantly higher than that of the other cases (2665 ± 685) died of liver failure (P < 0.005). FVI is a useful index to quantify residual liver functional reserve to avoid liver failure after major hepatectomy.

KW - Hepatic functional reserve

KW - Major hepatectomy

KW - Methionine Amino acid metabolism

UR - https://www.scopus.com/pages/publications/0030832457

U2 - 10.1016/S0928-4346(97)00371-X

DO - 10.1016/S0928-4346(97)00371-X

M3 - 記事

AN - SCOPUS:0030832457

SN - 0928-4346

VL - 7

SP - 43

EP - 47

JO - Hepatology Research

JF - Hepatology Research

IS - 1

ER -

Preoperative evaluation of residual liver function for extended hepatic resection with positron emission tomography and L-[methyl-¹¹C] methionine

Abstract

Keywords

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