Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma

Yukako Kawasaki; Masami Makimoto; Keiko Nomura; Akihiro Hoshino; Takeru Hamashima; Mitsuteru Hiwatari; Atsuko Nakazawa; Junko Takita; Taketoshi Yoshida; Hirokazu Kanegane

doi:10.1002/ccr3.183

Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma

Yukako Kawasaki
, Masami Makimoto
, Keiko Nomura
, Akihiro Hoshino
, Takeru Hamashima
, Mitsuteru Hiwatari
, Atsuko Nakazawa
, Junko Takita
, Taketoshi Yoshida
, Hirokazu Kanegane

University of Toyama
The University of Tokyo
National Center for Child Health and Development
Institute of Science Tokyo

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Key Clinical Message: We describe a neonate with abdominal distension, massive hepatomegaly, and high serum neuron-specific enolase level suggestive of congenital neuroblastoma. The patient died of pulmonary hemorrhage after therapy. Autopsy revealed that the tumor cells in the liver indicated acute megakaryocytic leukemia with the RBM15-MKL1 fusion gene.

Original language	English
Pages (from-to)	145-149
Number of pages	5
Journal	Clinical Case Reports
Volume	3
Issue number	3
DOIs	https://doi.org/10.1002/ccr3.183
State	Published - 1 Mar 2015
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

RBM15-MKL1
Acute megakaryoblastic leukemia
Neuroblastoma
Neuron-specific enolase

Access to Document

10.1002/ccr3.183

Cite this

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title = "Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma",

abstract = "Key Clinical Message: We describe a neonate with abdominal distension, massive hepatomegaly, and high serum neuron-specific enolase level suggestive of congenital neuroblastoma. The patient died of pulmonary hemorrhage after therapy. Autopsy revealed that the tumor cells in the liver indicated acute megakaryocytic leukemia with the RBM15-MKL1 fusion gene.",

keywords = "RBM15-MKL1, Acute megakaryoblastic leukemia, Neuroblastoma, Neuron-specific enolase",

author = "Yukako Kawasaki and Masami Makimoto and Keiko Nomura and Akihiro Hoshino and Takeru Hamashima and Mitsuteru Hiwatari and Atsuko Nakazawa and Junko Takita and Taketoshi Yoshida and Hirokazu Kanegane",

note = "Publisher Copyright: {\textcopyright} 2015 John Wiley \& Sons Ltd.",

year = "2015",

month = mar,

day = "1",

doi = "10.1002/ccr3.183",

language = "英語",

volume = "3",

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TY - JOUR

T1 - Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma

AU - Kawasaki, Yukako

AU - Makimoto, Masami

AU - Nomura, Keiko

AU - Hoshino, Akihiro

AU - Hamashima, Takeru

AU - Hiwatari, Mitsuteru

AU - Nakazawa, Atsuko

AU - Takita, Junko

AU - Yoshida, Taketoshi

AU - Kanegane, Hirokazu

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Key Clinical Message: We describe a neonate with abdominal distension, massive hepatomegaly, and high serum neuron-specific enolase level suggestive of congenital neuroblastoma. The patient died of pulmonary hemorrhage after therapy. Autopsy revealed that the tumor cells in the liver indicated acute megakaryocytic leukemia with the RBM15-MKL1 fusion gene.

AB - Key Clinical Message: We describe a neonate with abdominal distension, massive hepatomegaly, and high serum neuron-specific enolase level suggestive of congenital neuroblastoma. The patient died of pulmonary hemorrhage after therapy. Autopsy revealed that the tumor cells in the liver indicated acute megakaryocytic leukemia with the RBM15-MKL1 fusion gene.

KW - RBM15-MKL1

KW - Acute megakaryoblastic leukemia

KW - Neuroblastoma

KW - Neuron-specific enolase

UR - https://www.scopus.com/pages/publications/85019635538

U2 - 10.1002/ccr3.183

DO - 10.1002/ccr3.183

M3 - 記事

AN - SCOPUS:85019635538

SN - 2050-0904

VL - 3

SP - 145

EP - 149

JO - Clinical Case Reports

JF - Clinical Case Reports

IS - 3

ER -

Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma

Abstract

UN SDGs

Keywords

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