Impact of introduction of wire-guided cannulation in therapeutic biliary endoscopic retrograde cholangiopancreatography

Yousuke Nakai, Hiroyuki Isayama, Takeshi Tsujino, Naoki Sasahira, Kenji Hirano, Hirofumi Kogure, Takashi Sasaki, Kazumichi Kawakubo, Hiroshi Yagioka, Yoko Yashima, Suguru Mizuno, Keisuke Yamamto, Toshihiko Arizumi, Osamu Togawa, Saburo Matsubara, Natsuyo Yamamoto, Minoru Tada, Masao Omata, Kazuhiko Koike

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Background and Aim: Wire-guided cannulation (WGC) might increase the biliary cannulation rate and decrease the risk of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). We assessed the learning curve for WGC in therapeutic biliary ERCP (study 1) and compared WGC and conventional contrast-assisted cannulation (CC) by a matched case-control study (study 2). Methods: Prospectively collected data of 500 therapeutic biliary ERCP cases (250 consecutive cases of WGC and 250 matched controls of CC) were retrospectively studied. Rate and time of biliary cannulation, total procedure time, PEP, and hyperamylasemia were analyzed. Results: In study 1, biliary cannulation by WGC was successful in 96% of the first 50 cases, with a median time to cannulation of 3min. Rates of hyperamylasemia were within 10% after 100 WGC. In study 2, there were no significant differences in the overall cannulation rate and PEP between WGC and CC, but the total procedure time was shorter in WGC (30 vs 35min, P=0.059). Rates of hyperamylasemia and the change in serum amylase levels was lower (9% vs 14%, P=0.069, and +62.8U/L vs+169.5U/L, P=0.043) in WGC, which was more prominent in experienced endoscopists (9% vs 17%, P=0.025, and +68.9U/L vs+229.3U/L, P=0.014). Conclusions: The introduction of WGC was effective in the first 50 cases and did not increase the rate of PEP in biliary therapeutic ERCP.

Original languageEnglish
Pages (from-to)1552-1558
Number of pages7
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume26
Issue number10
DOIs
StatePublished - Oct 2011
Externally publishedYes

Keywords

  • Endoscopic retrograde cholangiopancreatography
  • Learning curve
  • Post-endoscopic retrograde cholangiopancreatography pancreatitis
  • Wire-guided cannulation

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