Evaluation of anti-diabetic drugs by using silkworm, Bombyx mori

Yasuhiko Matsumoto, Kazuhisa Sekimizu

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Since diabetes patients are increasing in the world, establishment of a novel method for development of anti-diabetic drugs is desired. In this review, we describe recent results of our studies regarding diabetic model using silkworms for evaluation of anti-diabetic drugs for patients of both type I and type II diabetes. The use of the evaluation systems using silkworms is expected to contribute to reduction in cost and in the number of mammals sacrificed for screening of anti-diabetic drugs.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalDrug discoveries & therapeutics
Volume10
Issue number1
DOIs
StatePublished - 2016
Externally publishedYes

Keywords

  • Anti-diabetic drugs
  • Diabetes
  • In vivo evaluation system
  • Silkworm

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