ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction

Sachiko Tsukita; Shigenobu Yonemura; Shoichiro Tsukita

doi:10.1016/S0968-0004(96)10071-2

ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction

Sachiko Tsukita, Shigenobu Yonemura, Shoichiro Tsukita

Kyoto University

Research output: Contribution to journal › Review article › peer-review

282 Scopus citations

Abstract

ERM (ezrin/radixin/moesin) proteins crosslink actin filaments with plasma membranes. The carboxyl termini of these proteins bind actin filaments, while the amino termini bind plasma membranes using a binding partner, such as CD44. Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway.

Original language	English
Pages (from-to)	53-58
Number of pages	6
Journal	Trends in Biochemical Sciences
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/S0968-0004(96)10071-2
State	Published - Feb 1997
Externally published	Yes

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10.1016/S0968-0004(96)10071-2

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title = "ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction",

abstract = "ERM (ezrin/radixin/moesin) proteins crosslink actin filaments with plasma membranes. The carboxyl termini of these proteins bind actin filaments, while the amino termini bind plasma membranes using a binding partner, such as CD44. Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway.",

author = "Sachiko Tsukita and Shigenobu Yonemura and Shoichiro Tsukita",

year = "1997",

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doi = "10.1016/S0968-0004(96)10071-2",

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AU - Tsukita, Sachiko

AU - Yonemura, Shigenobu

AU - Tsukita, Shoichiro

PY - 1997/2

Y1 - 1997/2

N2 - ERM (ezrin/radixin/moesin) proteins crosslink actin filaments with plasma membranes. The carboxyl termini of these proteins bind actin filaments, while the amino termini bind plasma membranes using a binding partner, such as CD44. Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway.

AB - ERM (ezrin/radixin/moesin) proteins crosslink actin filaments with plasma membranes. The carboxyl termini of these proteins bind actin filaments, while the amino termini bind plasma membranes using a binding partner, such as CD44. Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway.

UR - https://www.scopus.com/pages/publications/0031081475

U2 - 10.1016/S0968-0004(96)10071-2

DO - 10.1016/S0968-0004(96)10071-2

M3 - 総説

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AN - SCOPUS:0031081475

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JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

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ER -

ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction

Abstract

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