Endoscopic variceal ligation is a sufficient procedure for the treatment of oesophageal varices in patients with hepatitis C liver cirrhosis: Comparison with injection sclerotherapy

Yasuo Hata, Eiji Hamada, Morio Takahashi, Shinichi Ota, Keiji Ogura, Shuichiro Shiina, Makoto Okamoto, Tsuyoshi Okudaira, Takuma Teratani, Shin Maeda, Yukihiro Koike, Shinpei Sato, Shuntaro Obi, Torao Tanaka, Takao Kawabe, Yasushi Shiratori, Tateo Kawase, Masuyo Nomura, Masao Omata

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Aims: Endoscopic variceal ligation (EVL) is a recently developed alternative to endoscopic injection sclerotherapy (EIS) for the treatment of oesophageal varices. Endoscopic variceal ligation and EIS were compared in an attempt to clarify the efficacy and safety of EVL for patients with cirrhosis due to hepatitis C. Methods: Endoscopic variceal ligation was performed in 60 patients and EIS in 30. Varices were eradicated in all patients by EVL and 87% (26 out of 30) by EIS. Results: There was no significant difference between EVL and EIS in relation to the incidence of bleeding and the 5 year survival rate after treatment. There were no severe complications except mild substernal pain after EVL, while pulmonary embolism occurred in one patient receiving EIS. Conclusions: Endoscopic variceal ligation is a safe and effective technique for eradicating oesophageal varices in patients with hepatitis C cirrhosis.

Original languageEnglish
Pages (from-to)236-240
Number of pages5
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume14
Issue number3
DOIs
StatePublished - 1999
Externally publishedYes

Keywords

  • Endoscopic injection sclerotherapy
  • Endoscopic variceal ligation
  • Hepatitis C cirrhosis
  • Oesophageal varices

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