Abstract
Background: Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable.
Purpose: To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study.
Methods: Five individuals with chalazion and three patients with sebaceous carcinoma were observed. Noninvasive meibography was performed to visualize the reflectivity and shape of the lesion in each subject.
Results: Noninvasive meibographic imaging revealed chalazion as a lesion of overall low reflectivity with small regions of higher reflectivity corresponding to lipid granules. On the other hand, the noninvasive meibography revealed sebaceous carcinoma as a poorly marginated lesion of high reflectivity in the eyelid.
Conclusion: Noninvasive meibographic imaging may prove useful for the differential diagnosis of chalazion and sebaceous carcinoma. It may also be informative in definition of the resection area in carcinoma patients.
| Original language | English |
|---|---|
| Pages (from-to) | 1869-1875 |
| Number of pages | 7 |
| Journal | Clinical Ophthalmology |
| Volume | 8 |
| DOIs | |
| State | Published - 18 Sep 2014 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Chalazion
- Eyelid
- Noninvasive meibography
- Sebaceous carcinoma
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