Asymmetric synthesis of (+)-CP-99,994 and (+)-L-733,060 from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol

Tetsuta Oshitari; Tadakatsu Mandai

doi:10.1055/s-2006-956453

Asymmetric synthesis of (+)-CP-99,994 and (+)-L-733,060 from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol

Tetsuta Oshitari
, Tadakatsu Mandai

Kurashiki University of Science and the Arts

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Asymmetric syntheses of neurokinin substance P receptor antagonists (+)-CP-99,994 and (+)-L-733,060 have been accomplished starting from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol.

Original language	English
Pages (from-to)	3395-3398
Number of pages	4
Journal	Synlett
Issue number	20
DOIs	https://doi.org/10.1055/s-2006-956453
State	Published - 18 Dec 2006
Externally published	Yes

Keywords

1,2-Amino alcohols
1,2-Diamines
Hydroformylations
Neurokinin-1 antagonists
Piperidines

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10.1055/s-2006-956453

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title = "Asymmetric synthesis of (+)-CP-99,994 and (+)-L-733,060 from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol",

abstract = "Asymmetric syntheses of neurokinin substance P receptor antagonists (+)-CP-99,994 and (+)-L-733,060 have been accomplished starting from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol.",

keywords = "1,2-Amino alcohols, 1,2-Diamines, Hydroformylations, Neurokinin-1 antagonists, Piperidines",

author = "Tetsuta Oshitari and Tadakatsu Mandai",

year = "2006",

month = dec,

day = "18",

doi = "10.1055/s-2006-956453",

language = "英語",

pages = "3395--3398",

journal = "Synlett",

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AU - Oshitari, Tetsuta

AU - Mandai, Tadakatsu

PY - 2006/12/18

Y1 - 2006/12/18

N2 - Asymmetric syntheses of neurokinin substance P receptor antagonists (+)-CP-99,994 and (+)-L-733,060 have been accomplished starting from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol.

AB - Asymmetric syntheses of neurokinin substance P receptor antagonists (+)-CP-99,994 and (+)-L-733,060 have been accomplished starting from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol.

KW - 1,2-Amino alcohols

KW - 1,2-Diamines

KW - Hydroformylations

KW - Neurokinin-1 antagonists

KW - Piperidines

UR - https://www.scopus.com/pages/publications/33846551224

U2 - 10.1055/s-2006-956453

DO - 10.1055/s-2006-956453

M3 - 記事

AN - SCOPUS:33846551224

SN - 0936-5214

SP - 3395

EP - 3398

JO - Synlett

JF - Synlett

IS - 20

ER -

Asymmetric synthesis of (+)-CP-99,994 and (+)-L-733,060 from enantiomerically pure (3S,4S)-4-(tert-butylcarbamoyl)-4-phenyl-1-buten-3-ol

Abstract

Keywords

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