Anterograde amnesia by the illicit use of benzodiazepines

Keiko Shimizu; Osamu Saito; Kento Ogawa; Hajime Mizukami; Takashi Uezono; Hiroshi Shiono; Toshio Awaya; Yasuyuki Fujita; Kazuo Matsubara

Anterograde amnesia by the illicit use of benzodiazepines

Keiko Shimizu
, Osamu Saito
, Kento Ogawa
, Hajime Mizukami
, Takashi Uezono
, Hiroshi Shiono
, Toshio Awaya
, Yasuyuki Fujita
, Kazuo Matsubara

Asahikawa Medical University

Research output: Contribution to journal › Article › peer-review

Abstract

Recently, the criminal associated with the benzodiazepine combained with ethanol frequently occur in Japan. Memory deficits caused by taking benzodiazepine and ethanol are the point at issue. We investigated the mechanism of the anterograde amnesia to study in vivo hippocampal presynaptic glutamate transmission in conjunction with memory deficits induced by benzodiazepines and ethanol in rats as animal model of amnesia. We indicated that presynaptic dysfunction in dorsal hippocampal glutamatergic neurons would be critical for spatial memory deficits induced by benzodiazepines and ethanol.

Original language	English
Pages (from-to)	122-123
Number of pages	2
Journal	Japanese Journal of Forensic Toxicology
Volume	19
Issue number	2
State	Published - 2001
Externally published	Yes

Cite this

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abstract = "Recently, the criminal associated with the benzodiazepine combained with ethanol frequently occur in Japan. Memory deficits caused by taking benzodiazepine and ethanol are the point at issue. We investigated the mechanism of the anterograde amnesia to study in vivo hippocampal presynaptic glutamate transmission in conjunction with memory deficits induced by benzodiazepines and ethanol in rats as animal model of amnesia. We indicated that presynaptic dysfunction in dorsal hippocampal glutamatergic neurons would be critical for spatial memory deficits induced by benzodiazepines and ethanol.",

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T1 - Anterograde amnesia by the illicit use of benzodiazepines

AU - Shimizu, Keiko

AU - Saito, Osamu

AU - Ogawa, Kento

AU - Mizukami, Hajime

AU - Uezono, Takashi

AU - Shiono, Hiroshi

AU - Awaya, Toshio

AU - Fujita, Yasuyuki

AU - Matsubara, Kazuo

PY - 2001

Y1 - 2001

N2 - Recently, the criminal associated with the benzodiazepine combained with ethanol frequently occur in Japan. Memory deficits caused by taking benzodiazepine and ethanol are the point at issue. We investigated the mechanism of the anterograde amnesia to study in vivo hippocampal presynaptic glutamate transmission in conjunction with memory deficits induced by benzodiazepines and ethanol in rats as animal model of amnesia. We indicated that presynaptic dysfunction in dorsal hippocampal glutamatergic neurons would be critical for spatial memory deficits induced by benzodiazepines and ethanol.

AB - Recently, the criminal associated with the benzodiazepine combained with ethanol frequently occur in Japan. Memory deficits caused by taking benzodiazepine and ethanol are the point at issue. We investigated the mechanism of the anterograde amnesia to study in vivo hippocampal presynaptic glutamate transmission in conjunction with memory deficits induced by benzodiazepines and ethanol in rats as animal model of amnesia. We indicated that presynaptic dysfunction in dorsal hippocampal glutamatergic neurons would be critical for spatial memory deficits induced by benzodiazepines and ethanol.

UR - https://www.scopus.com/pages/publications/30844441202

M3 - 記事

AN - SCOPUS:30844441202

SN - 0915-9606

VL - 19

SP - 122

EP - 123

JO - Japanese Journal of Forensic Toxicology

JF - Japanese Journal of Forensic Toxicology

IS - 2

ER -

Anterograde amnesia by the illicit use of benzodiazepines

Abstract

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