Age dependence of diffusion-weighted magnetic resonance imaging findings in maple syrup urine disease encephalopathy

Mio Sakai, Yusuke Inoue, Hiroshi Oba, Akira Ishiguro, Kyoko Sekiguchi, Yoshihiko Tsukune, Masanori Mitomo, Hironobu Nakamura

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

A patient with maple syrup urine disease (MSUD) who developed encephalopathy twice and underwent magnetic resonance examinations, including diffusion-weighted (DW) imaging, is presented. Areas of abnormal intensity on DW images dramatically differed between the initial and second attacks, apparently attributable to the difference in myelination. Our observation demonstrates the age dependence of DW imaging findings in MSUD encephalopathy attributable to progression of myelination and would help in the proper diagnosis of MSUD encephalopathy at any age.

Original languageEnglish
Pages (from-to)524-527
Number of pages4
JournalJournal of Computer Assisted Tomography
Volume29
Issue number4
DOIs
StatePublished - 2005

Keywords

  • Diffusion-weighted imaging
  • Magnetic resonance imaging
  • Maple syrup urine disease

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