Acute Graft-versus-Host Disease of the Gut

Tohru Izumi; Youichi Amemiya; Noriaki Iwao; Toshiyuki Suzuki; Kazuo Muroi; Minoru Yoshida; Kiyohiko Hatake; Yasusada Miura; Noribumi Hitomi; Makio Hatakeyama; Kenji Nakazawa; Ken Saito

doi:10.2169/internalmedicine.34.751

Acute Graft-versus-Host Disease of the Gut

Tohru Izumi
, Youichi Amemiya
, Noriaki Iwao
, Toshiyuki Suzuki
, Kazuo Muroi
, Minoru Yoshida
, Kiyohiko Hatake
, Yasusada Miura
, Noribumi Hitomi
, Makio Hatakeyama
, Kenji Nakazawa
, Ken Saito

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 28-year-old man with acute promyelocytic leukemia at first early relapse received HLAmatched allogenic bone marrow transplantation (BMT) at first early relapse. Cyclosporin A and methotrexate were administered at conventional doses as a prophylaxis for graft-versus-host disease (GVHD). He presented with severe bloody diarrhea on day 87 after BMT. Examination of the lower gastrointestinal tract revealed diffuse mucosal change of inflammation. A diagnosis of late onset of acute gut GVHD was made, in the absence of other manifestations such as skin and liver involvement. A further survey is needed to clarify the incidence and the pathogenesis of atypical gut GVHD. (Internal Medicine 34: 751-755, 1995).

Original language	English
Pages (from-to)	751-755
Number of pages	5
Journal	Internal Medicine
Volume	34
Issue number	8
DOIs	https://doi.org/10.2169/internalmedicine.34.751
State	Published - 1995
Externally published	Yes

Keywords

acute promyelocytic leukemia (APL)
bone marrow transplantation (BMT)
colitis
lower gastrointestinal tract
T cell subset

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.34.751

Cite this

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title = "Acute Graft-versus-Host Disease of the Gut",

abstract = "A 28-year-old man with acute promyelocytic leukemia at first early relapse received HLAmatched allogenic bone marrow transplantation (BMT) at first early relapse. Cyclosporin A and methotrexate were administered at conventional doses as a prophylaxis for graft-versus-host disease (GVHD). He presented with severe bloody diarrhea on day 87 after BMT. Examination of the lower gastrointestinal tract revealed diffuse mucosal change of inflammation. A diagnosis of late onset of acute gut GVHD was made, in the absence of other manifestations such as skin and liver involvement. A further survey is needed to clarify the incidence and the pathogenesis of atypical gut GVHD. (Internal Medicine 34: 751-755, 1995).",

keywords = "acute promyelocytic leukemia (APL), bone marrow transplantation (BMT), colitis, lower gastrointestinal tract, T cell subset",

author = "Tohru Izumi and Youichi Amemiya and Noriaki Iwao and Toshiyuki Suzuki and Kazuo Muroi and Minoru Yoshida and Kiyohiko Hatake and Yasusada Miura and Noribumi Hitomi and Makio Hatakeyama and Kenji Nakazawa and Ken Saito",

year = "1995",

doi = "10.2169/internalmedicine.34.751",

language = "英語",

volume = "34",

pages = "751--755",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

number = "8",

}

TY - JOUR

T1 - Acute Graft-versus-Host Disease of the Gut

AU - Izumi, Tohru

AU - Amemiya, Youichi

AU - Iwao, Noriaki

AU - Suzuki, Toshiyuki

AU - Muroi, Kazuo

AU - Yoshida, Minoru

AU - Hatake, Kiyohiko

AU - Miura, Yasusada

AU - Hitomi, Noribumi

AU - Hatakeyama, Makio

AU - Nakazawa, Kenji

AU - Saito, Ken

PY - 1995

Y1 - 1995

N2 - A 28-year-old man with acute promyelocytic leukemia at first early relapse received HLAmatched allogenic bone marrow transplantation (BMT) at first early relapse. Cyclosporin A and methotrexate were administered at conventional doses as a prophylaxis for graft-versus-host disease (GVHD). He presented with severe bloody diarrhea on day 87 after BMT. Examination of the lower gastrointestinal tract revealed diffuse mucosal change of inflammation. A diagnosis of late onset of acute gut GVHD was made, in the absence of other manifestations such as skin and liver involvement. A further survey is needed to clarify the incidence and the pathogenesis of atypical gut GVHD. (Internal Medicine 34: 751-755, 1995).

AB - A 28-year-old man with acute promyelocytic leukemia at first early relapse received HLAmatched allogenic bone marrow transplantation (BMT) at first early relapse. Cyclosporin A and methotrexate were administered at conventional doses as a prophylaxis for graft-versus-host disease (GVHD). He presented with severe bloody diarrhea on day 87 after BMT. Examination of the lower gastrointestinal tract revealed diffuse mucosal change of inflammation. A diagnosis of late onset of acute gut GVHD was made, in the absence of other manifestations such as skin and liver involvement. A further survey is needed to clarify the incidence and the pathogenesis of atypical gut GVHD. (Internal Medicine 34: 751-755, 1995).

KW - acute promyelocytic leukemia (APL)

KW - bone marrow transplantation (BMT)

KW - colitis

KW - lower gastrointestinal tract

KW - T cell subset

UR - https://www.scopus.com/pages/publications/0029349191

U2 - 10.2169/internalmedicine.34.751

DO - 10.2169/internalmedicine.34.751

M3 - 記事

C2 - 8563115

AN - SCOPUS:0029349191

SN - 0918-2918

VL - 34

SP - 751

EP - 755

JO - Internal Medicine

JF - Internal Medicine

IS - 8

ER -

Acute Graft-versus-Host Disease of the Gut

Abstract

Keywords

UN SDGs

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