TY - JOUR
T1 - A case of advanced rectal cancer with severe liver dysfunction due to multiple liver metastases
AU - Higuchi, Tetsuro
AU - Ishikawa, Toshiaki
AU - Tsukamoto, Shunsuke
AU - Fujimori, Yoshitaka
AU - Oda, Goshi
AU - Okazaki, Satoshi
AU - Ishiguro, Megumi
AU - Kobayashi, Hirotoshi
AU - Iida, Satoru
AU - Uetake, Hiroyuki
AU - Yasuno, Masamichi
AU - Enomoto, Masayuki
AU - Sugihara, Kenichi
PY - 2009/11
Y1 - 2009/11
N2 - We report a case of rectal cancer with unresectable multiple liver metastases, which was worried about the transition from liver dysfunction to liver failure. The male patient in his 70s was diagnosed as advanced rectal cancer with severe liver dysfunction because of multiple liver metastases. Hepatic arterial infusion (HAI) chemotherapy, which was effective to reduce the size of metastatic liver tumors, was initially started. During HAI chemotherapy, sigmoid colostomy was performed. He recovered from liver dysfunction after he had been treated with 13th cycle HAI chemotherapy. He was treated with the modified FOLFOX6 regimen following a resection of rectal cancer. Although the standard therapy for colorectal cancer with unresectable liver metastases is firstly systemic chemotherapy such as FOLFOX or FOLFIRI, it might be better to control the liver metastases by HAI chemotherapy when a liver function is severely damaged by extensive liver tumors.
AB - We report a case of rectal cancer with unresectable multiple liver metastases, which was worried about the transition from liver dysfunction to liver failure. The male patient in his 70s was diagnosed as advanced rectal cancer with severe liver dysfunction because of multiple liver metastases. Hepatic arterial infusion (HAI) chemotherapy, which was effective to reduce the size of metastatic liver tumors, was initially started. During HAI chemotherapy, sigmoid colostomy was performed. He recovered from liver dysfunction after he had been treated with 13th cycle HAI chemotherapy. He was treated with the modified FOLFOX6 regimen following a resection of rectal cancer. Although the standard therapy for colorectal cancer with unresectable liver metastases is firstly systemic chemotherapy such as FOLFOX or FOLFIRI, it might be better to control the liver metastases by HAI chemotherapy when a liver function is severely damaged by extensive liver tumors.
KW - Hepatic arterial infusion chemotherapy
KW - Multiple liver metastases
KW - Rectal cancer
UR - https://www.scopus.com/pages/publications/84864575825
M3 - 記事
C2 - 20037363
AN - SCOPUS:84864575825
SN - 0385-0684
VL - 36
SP - 2181
EP - 2183
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 12
ER -
